clinical trial


Definition: Meaning of, clinical trial in English to English dictionary.

Pronunciation: / ˈklɪnɪk(ə)l ˈtrʌɪəl /

  • noun
  • synonym
  • antonym
Word Forms:
Singular Plural
clinical trial clinical trials
  1. a rigorously controlled test of a new drug or a new invasive medical device on human subjects; in the United States it is conducted under the direction of the FDA before being made available for general clinical use
    SYNONYM
    ANTONYM
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synonym
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clinical trial used in phrases

  • phase I clinical trial (noun)
    1. a clinical trial on a few persons to determine the safety of a new drug or invasive medical device; for drugs, dosage or toxicity limits should be obtained
  • phase II clinical trial (noun)
    1. a clinical trial on more persons than in phase I; intended to evaluate the efficacy of a treatment for the condition it is intended to treat; possible side effects are monitored
  • phase III clinical trial (noun)
    1. a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA
  • phase IV clinical trial (noun)
    1. sometimes the FDA approves a drug for general use but requires the manufacturer to continue to monitor its effects; during this phase the drug may be tried on slightly different patient populations than those studied in earlier trials
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